Evaluation of a measurement scale for assessing the extent of bleeding into the ventricles of the brain following a Haemorrhagic Stroke
Institution:Department of Cardiovascular and Medical Sciences, Western Infirmary Hospital, Glasgow
Principal Investigator:
Dr Matthew Walters
Country: Scotland
Grant value: £37,827.68 over 12 months
Status: ongoing
A bleed into the brain, Intracerebral haemorrhage (ICH), is serious and the chances of death can reach 80 per cent if bleeding into a part of the brain known as ventricles (IVH) occurs. At present we have no effective treatment for IVH, but removing the blood via a small drain placed into the ventricles looks promising.
Trials of this are underway but will require a simple way of measuring the extent of IVH on a brain scan. There is such a method, the Graeb scale, but we do not know how good it is or how it relates to outcome. We must understand this if we are to adequately interpret the trial results.
We will thoroughly evaluate the Graeb score and establish how useful it is using data from over 1,300 ICH cases contained within the Virtual International Stroke Trials Archive (VISTA). This is a vital step in testing a promising therapy for this devastating, untreatable condition.
Scientific title: The Impact of Intraventricular Haemorrhage on Functional Outcomes and Economic Cost of Stroke and Use of the Modified Graeb Scale to Evaluate Intraventricular Haemorrhage in a Large Randomised Controlled Trial
Classification:
Applied Neuroscience, Surgical Treatment