Gene linked to higher stroke and heart attack risk

Tuesday 1 July 2014

Researchers at King's College London have performed a large scale meta-analysis of previous research into a genetic variant of a protein implicated in stroke.  The meta-analysis, which takes into account the results of many previous studies, suggests that people who possess the genetic variant are at significantly increased risk of stroke caused by a blood clot. 

Dr Shamim Quadir, Research Communications Manager at the Stroke Association, said: “Findings from previous research investigating this genetic variant of a protein known as glycoprotein IIIa have been unclear. These latest results are an important step forward in stroke research. They suggest that people who possess this genetic variant known as PIA2 are at increased risk of stroke caused by a blood clot. 

“However, even if you have a family history of stroke, this does not mean that the condition is inevitable. Regular exercise, eating a balanced diet and stopping smoking can be important steps to significantly reduce your stroke risk.

“We hope the findings from this study could lead to many more people who are most at risk of this devastating condition being identified and treated. Understanding more about who is most at risk of stroke is essential in preventing as many strokes as possible in the future.”

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