Using a New Human Stem Cell Model to Understand the Causes of Stroke and to Test New Treatments

University of Cambridge
Status
Active
Summary

CADASIL is one of the most common genetic causes of stroke and dementia. Currently there is no treatment for CADASIL. In this study, human stem cells will be generated from a piece of skin donated by patients with CADASIL. From these stem cells, smooth muscle cells (SMCs) will be generated in a tissue culture dish in the lab. This work may pave the way for new treatments for CADASIL, and will allow us to better understand the ways that gene mutation causes disease.

Date published
01/09/2016

Understanding the importance of apathy, and improving its care in patients with stroke

University of Cambridge
Status
Active
Summary

Cerebral small vessel disease (SVD) is usually associated with high blood pressure, and causes 20% of all strokes. It is the main cause of cognitive changes and dementia associated with stroke. Behavioural symptoms such as apathy are also common in patients with SVD. This project will bring together a multidisciplinary team to better understand apathy after SVD, and potential treatments. 

Date published
18/03/2016

An investigation of whether functional strength training can improve the ability of stroke survivors to walk and use their arm and hand at least 1 year after stroke

University of East Anglia
Status
Closed
Summary

An investigation of whether functional strength training can improve the ability of stroke survivors to walk and use their arm and hand at least 1 year after stroke

Date published
14/01/2010

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