This research aims to improve outcomes for Intracerebral Haemorrhage (ICH) patients by developing new emergency treatments to reduce swelling in the brain after ICH, and improving the care they receive.
The number of patient-reported outcome measures (PROMS) has grown in the last few years. PROMs are questionnaires developed to accurately measure patients’ opinions about their health after an illness or during treatment. PROMs are used in both stroke research and routine stroke care.
After a stroke, some people have difficulty swallowing. Food and drink can go down the wrong way into the lungs instead of the stomach. This can cause a serious chest infection. The intended outcome of this project is to find new knowledge to help guide future policy on the reduction of chest infection risk after stroke.
This research project aims to better understand how particular features of the CT scan can be used to make better treatment decisions for patients with ischaemic stroke, and whether we can accurately estimate the time since the stroke began.
Magnetic resonance imaging (MRI) scans provide lots of data on the health of a person’s brain, not all of which is routinely used in clinical practice. This project will continue the development of tools to assess the brain scans of people with stroke. The outcome of this research should produce methods that can predict how patients will fare after a stroke, helping doctors to decide the best treatments and improve outcomes.
This study will investigate whether early initiation of direct anticoagulant drugs will be as safe as later initiation in stroke patients with an abnormal heart rhythm (atrial fibrillation). It will also investigate whether early initation could lead to fewer recurrent strokes.
About 80% of strokes are caused by a blocked blood vessel. One third of these patients have a blockage of a large blood vessel in the neck or brain known as large artery occlusion stroke (LAOS). The aim of this programme is to develop and test a new care pathway for paramedics to recognise those patients who are likely to have a large artery blockage, so that this group can be taken directly to the thrombectomy hospital.
Problems of mood, thinking and memory are common after a stroke. There has been limited research around these issues. This work aims to answer fundamental questions around who develops these problems and how they recover.
This study will investigate whether reducing blood pressure can stop bleeding in the brain after thrombolysis (a clot-busting treatment for stroke) and improve patient's outcomes.
Thrombolysis, where drugs are injected into the blood to break up a blood clot, is one of the main treatments used to treat people who are having a stroke caused by a clot. Currently a drug called alteplase is used in thrombolysis. But the researchers think that another drug, called tenecteplase, may be more effective than alteplase. This study will investigate if this is the case.