This research is focused on assessing the relationship between the variability of the blood flow through the blood vessels supplying the brain, and the risk of stroke in patients who have already had a stroke or “mini-stroke” (TIA) in the past.
Small Vessel Disease (SVD) is a disease of the small blood vessels in the brain and can lead to stroke and dementia. At the moment, we don't know how to stop SVD developing, or how to treat it. This Lectureship aims to improve future clinical trials that aim to prevent SVD.
In this study, we are testing the theory that by treating BP more intensively we will delay progression of the disease. We will also use state-of-the-art MRI imaging techniques to look at the mechanisms by which any beneficial effect of BP occurs.
Can using a tissue sample from the buttock help us understand the main genetic cause of stroke?
CADASIL is one of the most common genetic causes of stroke and dementia. Currently there is no treatment for CADASIL. In this study, human stem cells will be generated from a piece of skin donated by patients with CADASIL. From these stem cells, smooth muscle cells (SMCs) will be generated in a tissue culture dish in the lab.
This project is part of a larger on-going study into Small Vessel Disease (SVD) after stroke. It will allow the researchers to invite some of the participants in this project back for more frequent brain scans and tests to help them to understand more about SVD after stroke.
A haemorrhagic stroke is a stroke that is caused by bleeding in or around the brain. Although they are less common than strokes that are caused by a blockage, they can be much more serious.
Some aspects of women’s lives can increase our risk of a stroke, like the contraceptive pill, pregnancy and having migraines. But for most women, taking care of your health and managing your risk factors will help you avoid a stroke. Find out more about health conditions and medication linked to stroke in women, plus tips for healthy living.
The CROMIS-2 study investigated whether signs of small brain bleeds on routine brain scans can help us understand which ischaemic stroke patients with atrial fibrillation are at increased risk of a bleed in the brain when on anticoagulant ‘blood thinning’ drugs.