Existing vision tests do not tell us how a patient’s life will be influenced by their vision problems. This project aims to understand how the results of vision tests relate to how stroke survivors will be able to function in their daily lives.
This study will test arm training to encourage a functionally useful contribution to recovery from the side of the brain unaffected by stroke (the 'non-stroke hemisphere'), and whether this is only possible early after stroke.
No two strokes are alike - the damage from each stroke leaves its own unique signature on a person's brain and behaviour. The current project will investigate how different types of stroke affect a person's long term recovery or deterioration
Stroke survivors and their relatives consistently ask for information about how much recovery can be expected. This study will look at how well a patient can use their arm after stroke, and at their brain images recorded within 72-hours after stroke. The hope is that brain images can improve our prediction of patient arm movement recovery at six months after stroke.
The recovery of stroke survivors with language difficulties is famously variable. Some stroke survivors recover much more quickly or fully than others. Some respond to treatment much better than others.
Inflammation is an important defence mechanism that the body uses in response to injury or infection. However, it can also be highly damaging to the brain directly after stroke. This study will investigate whether adult stem cells can be transformed and used to reduce inflammation in the brain after stroke, and promote recovery.
The ReTrain study is investigating the effectiveness of a community-based rehabilitation training programme for people who have suffered a stroke. Published in the journal BMJ Open, the 'study protocol' for ReTrain outlines why the study was needed, and includes the methods to be used in the study, the resources required for the study and a timeline for completion.
Torpor is a natural state of reduced energy use and body temperature. This research will look at the effect of torpor on brain activity and function, and the amount of brain damage caused by ischaemic stroke.
The aim of this research is to develop and test a simple yet widely-applicable outcome measure for evaluating cognitive rehabilitation after stroke. Consultation with patients and carers will shape the design and content of the measure.
Small Vessel Disease (SVD) is a condition that affects the small blood vessels in the brain, and it can lead to stroke and dementia. This research programme hopes to increase our understanding of how SVD develops, leading to new ways to investigate SVD and test drugs which may help treat it.