This study will investigate whether adult stem cells can be transformed and used to reduce inflammation in the brain after stroke, and promote recovery.
Inflammation following stroke is highly damaging to brain cells. Can stem cells be used to reduce the damage of inflammation after stroke and promote brain repair?
Published in the journal, The Lancet, the findings of the PISCES I study shed more light on the potential use of stem cell treatment for stroke.
Dr Shamim Quadir, Research Communications Manager at the Stroke Association comments.
Published in the medical journal Stroke, a new US study suggests that treatment of chronic stroke patients with injections of modified, adult stem cells into their brains is safe, and could lead to recovery of movement that was originally lost due to stroke.
Thousands of lives a year could be changed thanks to a pilot research study by Imperial College which involves injecting a patient's stem cells into their brain.
Sickle cell disease (SCD) is an inherited condition that affects red blood cells. There are several different types of sickle cell disease, with a range of symptoms. It can increase the risk of a stroke, especially in young children. Young people and adults are also more likely to have a stroke. Stroke is more common with certain types of SCD.
In this study, human stem cells will be generated from a piece of skin donated by patients with CADASIL. This could create new treatments for CADASIL, and allow us to better understand the way that gene mutation causes disease.
A stroke in the brain stem can cause the very rare condition of locked-in syndrome, where the person is conscious but unable to move apart from their eyes.
This study will examine some of the biological pathways involved when blood in the brain causes brain cells to die.
Developing new blood tests to understand more about children with sickle cell anaemia and silent strokes.