This research project aims to better understand how particular features of the CT scan can be used to make better treatment decisions for patients with ischaemic stroke, and whether we can accurately estimate the time since the stroke began.
People with stroke due to brain haemorrhage have swelling around the haemorrhage on their brain scan. More swelling worsens recovery. No treatment improves outcome after this swelling.
The programme will use biological information about cells and molecules, and information from patients, to design a study of treatment for swelling after a brain haemorrhage.
The aim of this research programme is to develop a human brain bank to support biomedical research into the pathophysiology of human SVD that may be used nationally and internationally.
Existing vision tests do not tell us how a patient’s life will be influenced by their vision problems. This project aims to understand how the results of vision tests relate to how stroke survivors will be able to function in their daily lives.
The recovery of stroke survivors with language difficulties is famously variable. Some stroke survivors recover much more quickly or fully than others. Some respond to treatment much better than others.
Magnetic resonance imaging (MRI) scans provide lots of data on the health of a person’s brain, not all of which is routinely used in clinical practice. This project will continue the development of tools to assess the brain scans of people with stroke.
People who have survived a previous stroke or transient ischaemic attack (TIA) are at particularly high risk of subsequent, ‘recurrent’ stroke with 30% having another stroke in the following five years. High blood pressure is the most important reversible risk factor for having a recurrent stroke.
Inflammation is an important defence mechanism that the body uses in response to injury or infection. However, it can also be highly damaging to the brain directly after stroke. This study will investigate whether adult stem cells can be transformed and used to reduce inflammation in the brain after stroke, and promote recovery.
This study will investigate whether early initiation of direct anticoagulant drugs will be as safe as later initiation in stroke patients with an abnormal heart rhythm (atrial fibrillation). It will also investigate whether early initiation could lead to fewer recurrent strokes.
Speech and language therapy (SLT) may help stroke patients with communication difficulties recover but there is a lack of evidence-based treatments available. This study aims to address the need for evidence-based treatments and improve clinical expertise to address problems with everyday conversation after stroke.