Stroke survivors and their relatives consistently ask for information about how much recovery can be expected. This study will look at how well a patient can use their arm after stroke, and at their brain images recorded within 72-hours after stroke. The hope is that brain images can improve our prediction of patient arm movement recovery at six months after stroke.
Inflammation is an important defence mechanism that the body uses in response to injury or infection. However, it can also be highly damaging to the brain directly after stroke. This study will investigate whether adult stem cells can be transformed and used to reduce inflammation in the brain after stroke, and promote recovey.
Pain in the shoulder is a common problem after stroke. As well as causing distress through pain and lost sleep, it prevents rehabilitation of the arm and hand. This study will identify ‘who’, ‘when’ and ‘how’ to treat people with painful shoulders after stroke more effectively, and should lead to better outcomes for them.
Spatial neglect is caused when damage to the brain after stroke means that it no longer received information about one side of the body and/or world. Stroke survivors with spatial neglect might not be aware of anything happening on one side of their body. This research will investigate a computer based version of a new treatment for spatial neglect after stroke.
A panel of independent experts has decided that alteplase, a clot-busting drug often used to treat strokes is safe and effective under current guidelines.
This study will investigate whether early initiation of direct anticoagulant drugs will be as safe as later initiation in stroke patients with an abnormal heart rhythm (atrial fibrillation). It will also investigate whether early initation could lead to fewer recurrent strokes.
Comparing two treatment strategies in patients with visual problems after stroke
Torpor is a natural state of reduced energy use and body temperature. This research will look at the effect of torpor on brain activity and function, and the amount of brain damage caused by ischaemic stroke.
Vascular dementia is the 2nd leading cause of dementia in the UK and there are currently no proven treatments. A new study at the University of Southampton is now investigating whether a failure of fluid drainage along the walls of blood vessels in the brain is a cause of vascular dementia.