What is the role of the brain's waste clearance system in small vessel disease?
Dr Michael Stringeri s researching why some stroke survivors with small vessel disease go on to experience more brain damage than others.
How can we maximise a brain bank resource to help small vessel disease?
Professor Colin Smith and his team are developing a brain bank which can support national and international research on small vessel disease and its links to stroke and thinking and memory problems
Failure of drainage of fluid from the brain along the walls of blood vessels in vascular dementia
This project aims to demonstrate that failure of drainage of fluid from the grey and white matter of the brain is a mechanism underlying Small Vessel Disease, a condition that affects the small blood vessels in the brain which can cause stroke and dementia.
SVD-SOS: Patient-focused trials for cerebral small vessel disease
This project is part of a larger on-going study into Small Vessel Disease (SVD) after stroke. It will allow the researchers to invite some of the participants in this project back for more frequent brain scans and tests to help them to understand more about SVD after stroke.
Developing new models to better understand and allow testing of new therapies for small vessel disease and vascular dementia
Small Vessel Disease (SVD) is a condition that affects the small blood vessels in the brain, and it can lead to stroke and dementia. This research programme hopes to increase our understanding of how SVD develops, leading to new ways to investigate SVD and test drugs which may help treat it.
Understanding the importance of apathy, and improving its care in patients with stroke
Cerebral small vessel disease (SVD) causes 1 in 5 strokes. People who have SVD also commonly have apathy - a loss of interest and initiative. In this project, Professor Hugh Markus brings together a multidisciplinary team to better understand what is happening in the brains of people with SVD who are experiencing apathy, and how it could be treated.
How to improve trials of new treatments for stroke and dementia
Small Vessel Disease (SVD) is a disease of the small blood vessels in the brain and can lead to stroke and dementia. At the moment, we don't know how to stop SVD developing, or how to treat it. This Lectureship aims to improve future clinical trials that aim to prevent SVD.