Published online (ahead of print in the journal Annals of Neurology), the results of a new study found that one year after arterial ischaemic stroke (AIS), the rate of death, recurrence of stroke, and neurological impairment was lower than reports in previous studies.
About 80% strokes are caused by a blocked blood vessel. One third of these patients have a blockage of a large blood vessel in the neck or brain known as large artery occlusion stroke (LAOS).
If we are to discover which underlying genes cause stroke, we need to collect DNA from large numbers of patients who have had a lacunar stroke. An existing collection of DNA (extracted from blood samples) from patients has been established with the aid of a Wellcome Trust grant, this is called the UK Young Lacunar Stroke DNA Database.
Intracerebral haemorrhage (ICH) is a type of stroke, which is caused by bleeding in the brain, ultimately leading to brain damage, disability and often death. We currently know very little about the biological changes that occur in the brain after intracerebral haemorrhage.
Pilot trial of devices to extract clot from occluded arteries (PISTE)
Co-funded by the Stroke Association, the only project of its kind anywhere that studies all acute vascular events, such as strokes and heart attacks, to develop better treatments has recruited its 10,000th Oxfordshire participant.
Stroke Association/BHF Joint Programme Grant
This research programme could substantially increase our understanding of how SVD develops, leading to new ways to investigate SVD and test drugs which may help treat it.
Cerebral small vessel disease (SVD) is usually associated with high blood pressure, and causes 20% of all strokes. It is the main cause of cognitive changes and dementia associated with stroke. Behavioural symptoms such as apathy are also common in patients with SVD.