Exploring the effects of lowering blood pressure and a lower dose of clot busting drug on stroke outcome
Funded by the European Union (EU), a new international study called PROOF will investigate whether high-dose oxygen therapy can reduce the effects of stroke.
The Stroke Association is a member of the Stroke Alliance For Europe (SAFE), which will work on communication of information about the PROOF trial to non-clinical audiences.
Promising research results for a new drug treatment for ischaemic stroke patients have been published today in the journal ‘Lancet Neurology’.
Most stroke and transient ischaemic attack (TIA) survivors are asked to take medicines, which some can find difficult. However, taking the medicines prescribed after a stroke, or TIA, and following lifestyle advice can reduce the chance of another stroke by 80%. Unfortunately, over 25% of stroke survivors do not continue these medicines, even for the first year after their stroke. Another 20% take less than is needed for the medicines to work.
This research will use the views of stroke and TIA survivors to design a life-long medicines support service which could be provided by pharmacists.
This study will show whether more intensive lowering of blood pressure (BP) in survivors of intracerebral haemorrhage (ICH) is feasible, safe and effective in reducing brain injury. If successful, the study will pave the way for the design a larger definitive trial.
Carotid artery narrowing causes about 15% of strokes of the type where blood clots block blood flow to the brain, and this study aims to find prevention for this.