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Using genetics to understand why disease of the small blood vessels in the brain occurs.

In this study, human stem cells will be generated from a piece of skin donated by patients with CADASIL. This could create new treatments for CADASIL, and allow us to better understand the way that gene mutation causes disease.

The Stroke Association is part of the Patient and Public Involvement Strategy, led by Dr Ava Easton on a grant worth £2.3 million to investigate the neurological and neuropsychiatric effects of COVID-19.

Cerebral venous thrombosis (CVT) is an unusual form of stroke. The study will provide a much better understanding of the reasons underlying CVT, which is an unusual but very important cause of stroke in young (mainly female) adults.

These summaries of our completed research projects highlight what work was undertaken, which aims were achieved and where the research is going next.