Getting the most from brain MRI scans: new and better measures of brain health in stroke
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Magnetic resonance imaging (MRI) scans provide lots of data on the health of a person’s brain, not all of which is routinely used in clinical practice. This project will continue the development of tools to assess the brain scans of people with stroke. The outcome of this research should produce methods that can predict how patients will fare after a stroke, helping doctors to decide the best treatments and improve outcomes.
Post stroke fatigue investigation using transcranial magnetic stimulation and functional magnetic resonance imaging
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Testing the idea that fatigue occurring after stroke is due to changes in the brain regions controlling the muscles using non-invasive brain stimulation and brain imaging techniques in 142 stroke patients, half of who will be those who complain of fatigue.
How intensively should we treat blood pressure in patients with disease of the small blood vessels in the brain?
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In this study, we are testing the theory that by treating BP more intensively we will delay progression of the disease. We will also use state-of-the-art MRI imaging techniques to look at the mechanisms by which any beneficial effect of BP occurs.
Developing new technologies for stroke treatment
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Our charity collaborated with SBRI Healthcare and the AHSN Network to fund innovations in technologies to improve diagnosis and rehabilitation of stroke.
Profiling chronic and recovered language comprehension networks post stroke: Psychoacoustic, neuropsychological and fMRI investigations.
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We are yet to understand the differences between those individuals who do and do not spontaneously recover language comprehension abilities. This research aims to uncover these differences.
Can we improve predictions of upper limb recovery after stroke with brain imaging?
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This study will look at how well a patient can use their arm after stroke, and at their brain images recorded within 72-hours after stroke.
Can the type and extent of stroke and its impact on behaviour predict dementia?
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No two strokes are alike - the damage from each stroke leaves its own unique signature on a person's brain and behaviour. The current project will investigate how different types of stroke affect a person's long term recovery or deterioration
Can we predict how people with aphasia after stroke will respond to speech and language therapy?
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The project aims to employ similar techniques to the PLORAS project to predict which patients are most suited to which speech and language therapy.
Using transcranial magnetic stimulation (TMS) to enable activation of the damaged part of the brain to be more active in the recovery period after a stroke
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Using transcranial magnetic stimulation (TMS) to enable activation of the damaged part of the brain to be more active in the recovery period after a stroke