In this project, the aim is to demonstrate that failure of drainage of fluid from the grey and white matter of the brain is a mechanism underlying SVD.
This research programme could substantially increase our understanding of how SVD develops, leading to new ways to investigate SVD and test drugs which may help treat it.
A collaboration of experts in stroke and vascular dementia has worked with people affected by both diseases to create a program of work that answers fundamental questions: who will develop memory and thinking problems after stroke, why does this happen, how can we treat it?
Beyond impaired language function, people with aphasia report a range of psychosocial health problems which negatively affect their wellbeing, including reduced confidence and social isolation. These psychosocial problems are not adequately addressed by healthcare services. This study will pilot a new group-based singing intervention for improving the psychosocial health of people with aphasia.
As well as reducing independence, walking problems after stroke lead to lower daily activity, increasing risk of further stroke and health problems. A promising method of improving walking after stroke is through ‘auditory rhythmical cueing.’ which involves people walking to the rhythm of a sound beat. This method improves walking after stroke in the hospital, but has not been tested later on at home where recovery could continue.
Cerebral venous thrombosis (CVT) is an unusual form of stroke. It is little researched largely because it accounts for less than 1% of all strokes. The study will provide a much better understanding for the reasons underlying CVT, which is an unusual but very important cause of stroke in young (mainly female) adults. It could lead to a better prediction of who will have a CVT, as well as to discovery of specific treatments.
Disease of the chest portion of the largest artery in the body (the aorta), is known as thoracic aortic disease (TAD). The number of people experiencing TAD is increasing. This study is investigating how to make thoracic endovascular aortic stenting (TEVAR), the preferred method of treating TAD, safer by using extra protection devices.
About one third of stroke survivors acquire aphasia. This is a language disorder that disrupts the production and comprehension of speech, as well as reading and writing. This study will investigate whether a support group intervention can be delivered remotely to people with aphasia through a virtual island platform called Eva Park.
No two strokes are alike - the damage from each stroke leaves its own unique signature on a person's brain and behaviour. The current project will investigate how different types of stroke affect a person's long term recovery or deterioration
This study will explore whether an existing therapy, Solution Focused Brief Therapy (SFBT), can be used for people with aphasia. Information will also be collected to design a future large-scale trial evaluating this approach.